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Dangerous Drugs and Drug Abuse in the News

Today is Monday June 21, 2010

Latin American Women Turn to Cheap Ulcer Drug to End Pregnancies

March 19, 2003 - Frustrated by governments that outlaw abortion, Latin American women are turning to a cheap ulcer medication to end unwanted pregnancies, according to a March 19, 2003 story by Associated Press writer Andres Cala.

She wrote that some pharmacies in the Dominican Republic sell as much Cytotec as aspirin or cold remedies, according to the Dominican Pharmacy Owners' Association.

"No one yet knows the best ways to use it but ... where abortion is illegal and unsafe, it might be the single safest method," said Dr. Beverly Winikoff, director of reproductive health for the New York-based Population Council.

Cytotec came onto the market in the late 1980s as an anti-ulcer drug but its unapproved use as an abortive aid has grown, particularly in countries where abortions carry prison terms of up to 20 years.

Anti-abortion groups are fighting to get the drug off the market, saying it amounts to legalized abortion, according to the AP report.

"The Catholic Church radically condemns any sort of abortion," said the Rev. Nelson Acebedo, secretary of the archdiocese of Santo Domingo. "It doesn't matter if the abortion is done by taking some medicine, we equally condemn it."

But for some women, Cytotec provides a choice, stated Cala..

"This country made me feel that what I was (considering) was evil," said 34-year-old Digna, who did not want her last name published.

A mother of two, she turned to Cytotec five years ago when she became pregnant. Strapped for cash and in a bad relationship, a friend bought the tiny pills at a pharmacy for $1 each and, in three days, Digna miscarried in her mother's bathroom with no complications. Women take from eight to 16 pills. Illegal surgical abortions here can cost from $400 to $1,000.

Cytotec, known generically as misoprostol, is often taken in conjunction with mifepristone, also known as RU-486, which blocks a hormone vital for embryo development. But mifepristone is banned in countries where abortion is illegal, and Cytotec is taken alone.

The ulcer drug is "pretty safe and effective" and causes contractions resulting in the expulsion of an embryo 80 to 95 percent of the time, said Dr. Philip D. Darney, professor of obstetrics and gynecology at the University of California, San Francisco.

He is co-author of an article in the New England Journal of Medicine that cites risks as hemorrhaging and infection, and the most common side effects as nausea, abdominal pain, chills and fever.

Women who have had Caesarean sections also risk rupturing scar tissue and their uterus, said Dr. Charles Lockwood, chairman of the obstetrics and gynecology department of Yale University School of Medicine.

But "it is still far safer than illegal or unskilled surgical abortions," said Dr. Laura MacIsaac, assistant professor of obstetrics and gynecology and director of family planning at Albert Einstein College of Medicine in New York City.

Cytotec's maker, New Jersey-based Pharmacia Inc., defends its product for its labeled use as a gastric drug and points to a warning cautioning pregnant women of its side-effects.

But lax legislation, lack of control, and the drug's popularity in Latin America make it easy to get without a prescription.

With the exception of Cuba and the U.S. Caribbean territory of Puerto Rico, abortion is illegal in Latin America. About 4 million illegal surgical abortions are performed every year — 6,000 of which result in women's deaths, according to the World Health Organization (news - web sites).

 

 

Contraceptives are widely available but most women don't use them because they don't have the money or because it's unacceptable in their culture or religion. And men are reluctant to use condoms.

In Peru, one in three pregnancies is terminated, according to the Flora Tristan women's rights group, and Cytotec has helped reduce hospitalizations linked to unsafe surgical abortions.

The group conducted a study last year that indicated one in seven illegal abortions in Peru led to hospitalization.

Cytotec is widely available, and Colombia and Brazil are making a generic version — labeled only as an ulcer drug.

"It is simply irresponsible that the government prohibits abortion without giving out information," Digna said. "They know it happens daily, so they'd better just deal with it and inform women."

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